Changing social behavior by modifying genes! Are we witnessing the modeling of generations modified in behavior? … Jordan

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A broad moral banner aimed at improvement and perfection to rule out socially disadvantaged behaviors and find medical solutions to dilemmas like schizophrenia, depression and autism, but along the way the balance is broken and the results are the opposite and it seems real. scary. So what is the story?

Beginning: odorless stray ants

Behavior can be changed, but hearts cannot be changed, so (the heart of a prophet) and unstable behavior, is a thousand times easier than the heart of a demon, and behavior that resembles the behavior of a prophet! * Jalal Khawaldeh, “Luck, love, hope … and other things”

An experiment conducted by researcher Danny Rheinberg and his colleagues to modify the genes of an ant species, so that it loses its sense of smell, which results in profound distortions in the behavior and brain of ants, while females wander to alone, refuse to mate. , and live separate from their normal social life. Genetically modified ants have proven the importance of the sense of smell in the maintenance of insect societies, and perhaps the most prominent sentence in the experiment was that of Rheinberg: “The ant seemed to be wandering as if it were walking in a land of wonders.”

He said: “In a broad sense, these studies indirectly suggest that the human brain may also be subject to this type of stereotype, and a good understanding of biochemistry, how behavior is formed can reveal knowledge about disorders in it. which changes in social communication are a hallmark of schizophrenia, depression and others.

Less testosterone = more femininity

“Changing societies to the strongest is a moral difference, whose advocates must adhere to human behavior away from dictatorial ideas by annulling the ideas of others.” * Muhammad Shihab al-Din Arabi, “Renewed Hostility and Missing Justice – Political Readings in Both Directions.” ”

He conducted his experiments on highly social African cichlids, using advanced techniques such as single-cell genomics, whole-brain development, and social behavior patterns, to see how testosterone really regulates male behavior and consequently social behavior. Excessive presence leads to aggressive behavior and irritability.

In fact, Allward used CRISPR / Cas9 technology, or “gene scissors,” to delete specific receptors in order to obtain mutated males. “Mutated men actually perform typical female behaviors,” Elward said.

While the research that began in 2021 is still a work in progress, Eluard seemed confident of the expected results of his work. He said: “We will be able to address basic questions related to hormonal control of the brain and social behavior, and these questions can naturally be related to those related to hormonal control of social behavior, in other species, such as humans. , and how social systems evolve over evolution.

Counterproductive and also dangerous!

“The target was the less aggressive animals, but the result was the opposite. We did not understand this system as we thought we did!”

Study based entirely on it.

The research team, led by Neuroscience Professor Elliot Albers and Honorary Professor Kim Hohmann University, used CRISPR-Cas9 technology, a technology used in a wide range of applications such as biological and medical research, biotechnology product development and treatment of diseases. eliminate the effect of neurochemical signaling pathway activity, which plays an important role in regulating social behaviors in mammals.

Well, the hormone vasopressin controls a receptor called Avpr1a, which controls social phenomena like marriage, cooperation, socialization, domination and aggression, so what if the Avpr1a receptors in hamsters are eliminated and the effect of vasopressin is eliminated? Of course – and according to theoretical hypotheses – social behavior will change radically, reducing violence and aggression, as well as social communication, but the opposite has happened! Modified and receptor-free hamsters showed higher levels of social communication as well as aggression.

It is worth noting that the importance of the hamster is increasing in social behavior studies, as it is closest to humans in the hormonal response to stress; Hamsters secrete the hormone cortisol in response to stress, just like the average human, but the results of the study confirmed that “social behavior is more complex than previously thought.”

Researchers in China to modify genes into an unfeasible human embryo, with the stated intention of “curing inherited blood disease”, but they ended up with many changes that they said were “unintentional” and also dangerous, to the point that scientists. researcher and a high-level group of researchers called And ethics in Washington to discuss the ethics of gene editing!

At the time, it sounded very scary. The researchers said they were “concerned about changes in the eggs, sperm or embryos of humans known as the human germ line. In the egg and sperm of the baby, and then the genetic changes that are inherited.” That is why the organizing committee at the time ended the discussion with a statement saying: “It would be irresponsible to continue with any clinical use of germline modification until further safety and efficacy research is performed and the risks and benefits are weighed. . “

More research and funding is on the way

“Genes do not determine your destiny, they determine the range of possibilities.” James Clear

The Nobel Prize in Chemistry is awarded to Emmanuel Charbontier and Jennifer Doudna for their success in developing CRISPR-Cas9 technology, a technology that revolutionized genetics because it allows the modification and modification of organisms’ DNA, or what is known as “genetic scissors”.

A set of penetrating ideas led to the creation of an unprecedented technology that conquered the scientific community and revolutionized the field of genetic research, enabling scientists to perform highly accurate operations on the DNA of plants, animals, and humans. An easy way to rewrite the genetic code of an organism, in which parts of the genetic material are removed or inserted with the utmost precision, and can also be used to inactivate genes, correct abnormalities, or insert genes to simulate human genetic diseases in laboratory animals.

The development of hormonal behavioral relationships and the effect of hormones such as oxytocin, vasopressin and others on the regulation of social behaviors, which occurs each time limiting or eliminating the receptors for these hormones in the brain.

Their 2020 study, Arjen J. Bowander and Larry J. Young, conclude that new technologies are capable of unprecedented interrogation of genes and behaviors that regulate neural circuits, which requires genetically modified models. To date, rats have been used to examine gene roles and enable dissection and manipulation of nerve circuits by observing activities and regulations that regulate behaviors, while the study ended by encouraging more researchers and funding agencies to this end.

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Viewing social behavior that changes by modifying

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